The nature of transtubular Na and K transport in isolated rabbit renal collecting tubules
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چکیده
منابع مشابه
Paths of Transtubular Water Flow in Isolated Renal Collecting Tubules
The cells of perfused rabbit collecting tubules swell and the intercellular spaces widen during osmotic flow of water from lumen to bath induced by antidiuretic hormone (ADH). Ouabain had no influence on these changes. In the absence of net water flow intercellular width was unaffected when tubules were swollen in hypotonic external media. Therefore, during ADH-induced flow widening of intercel...
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Isolated cortical collecting tubules from rabbit kidney were studied during perfusion with solutions made either isotonic or hypotonic to the external bathing medium. Examination of living tubules revealed a reversible increase in thickness of the cellular layer, prominence of lateral cell membranes, and formation of intracellular vacuoles during periods of vasopressin-induced osmotic water tra...
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Inorganic phosphate and sulfate are the major divalent anions in biological fluids at physiological pH. The isolated perfused renal tubule technique has been used to address a number of questions about their renal transport; the purpose of this review is to summarize this information. Initial studies addressed traditional questions about the direction and segmental localization of phosphate and...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1970
ISSN: 0021-9738
DOI: 10.1172/jci106399